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NAD+

NAD+

Cellular energy and longevity

$350/mo

Virtual consult required

This peptide requires a brief virtual visit before our team can prescribe.

Details

Virtual Consult

Our licensed provider reviews your health profile via secure video — typically 10 minutes. Required for any peptide prescription.

Refund Policy: If found not eligible due to health reasons after consultation, you will receive a full refund.

Product Details

About NAD+

Mechanism of Action

NAD+ is a critical coenzyme functioning as an electron carrier in mitochondrial ATP production. It's essential for sirtuins (SIRT1-7), which regulate DNA repair, inflammation, and metabolism, and for PARPs that repair damaged DNA. NAD+ levels decline ~50% between ages 40-60, contributing to mitochondrial dysfunction and virtually all hallmarks of aging.

Scientific Background

Research by Dr. David Sinclair and others has revealed NAD+ as a master regulator of aging. Animal studies show boosting NAD+ can extend lifespan, improve physical performance, and reverse cellular aging. Depletion is implicated in neurodegenerative diseases, metabolic syndrome, cardiovascular disease, and cancer.

Clinical Applications

Used for anti-aging, cognitive enhancement, addiction recovery, and chronic fatigue. IV infusions provide rapid increases in cellular NAD+, often with immediate effects on energy and mental clarity. Also shows promise for neurological health, TBI recovery, and metabolic optimization. Subcutaneous injection offers convenient alternative to IV.

Evidence-Based

Clinical Research & Studies

Backed by peer-reviewed research from leading medical journals

2019
Peer Reviewed

NAD+ decline and aging: mechanisms and therapeutic potential

Comprehensive review demonstrating NAD+ levels decline with age across multiple tissues, contributing to mitochondrial dysfunction and age-related diseases, while NAD+ replenishment shows promise for extending healthspan.

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2017
Peer Reviewed

NAD+ supplementation normalizes key Alzheimer's features and DNA damage responses

Study showing NAD+ augmentation reduces DNA damage, inflammation, and neuron death in Alzheimer's disease models, suggesting therapeutic potential for neurodegenerative conditions.

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2016
Peer Reviewed

Long-term NMN administration mitigates age-associated functional decline

Research demonstrating that NAD+ precursor supplementation in aged mice restores multiple age-related physiological declines including energy metabolism, insulin sensitivity, and physical performance.

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Educational Articles

Article

NAD+ Therapy: The Ultimate Guide to Cellular Rejuvenation

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Article

Understanding NAD+ and Longevity: Science-Based Anti-Aging

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